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U.S. Department of Health and Human Services

GRAS Notices
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GRN No. 1271

Short-chain fructooligosaccharides

Intended Use: Intended for use as an ingredient in cow-milk based, non-exempt infant formula for term infants at a level, as consumed, up to 400 mg scFOS/100 mL formula for infants 0-6 months of age and up to 500 mg scFOS/100 mL formula for infants >6 months of age. The intended use of scFOS also includes as a bulking agent and ingredient in the same food categories and use levels as in GRN 001006.
Basis: Scientific procedures
Notifier: Tate and Lyle
Notifier Address: 5450 Prairie Stone Parkway
Hoffman Estates, IL 60192
GRAS Notice (releasable information): GRN 1271 (in PDF) (3.4 MB)
  Part 2: GRN 1271 amendments (in PDF) (3.7 MB)
Date of closure: Mar 18, 2026
FDA's Letter: FDA has no questions (in PDF) (234 kB)
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