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U.S. Department of Health and Human Services

GRAS Notices
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GRN No. 1285

Saccharomyces cerevisiae BY-927 expressing a gene encoding α-acetolactate decarboxylase enzyme from Acetobacter aceti

Intended Use: Intended for use in beer brewing at a level of 7.5 x 105 1.5 x 106 cells per mL per degree Plato of wort to improve beer flavor by preventing the formation of diacetyl.
Basis: Scientific procedures
Notifier: Berkeley Fermentation Science Inc.
Notifier Address: 15555 E 14th Street, Suite 525
San Leandro, CA 94578
GRAS Notice (releasable information): GRN 1285 (in PDF) (2.1 MB)
  Part 2: GRN 1285 amendment (in PDF) (102 kB)
Date of closure: Mar 9, 2026
FDA's Letter: FDA has no questions (in PDF) (255 kB)
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