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U.S. Department of Health and Human Services

Cumulative Estimated Daily Intake (CEDI)

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POLYSORBATE 80

CAS Reg. No. (or other ID*): 9005-65-6
Substance: POLYSORBATE 80
Cumulative Estimated Daily Intake (CEDI): 2750 µg/kg bw/d
Cumulative Dietary Concentration (CDC): 55000 ppb
Calculation/update date: Oct 22, 2010
Other names: ♦ POLYSORBATE 80
♦ GLYCOLS, POLYETHYLENE, ETHER WITH SORBITAN MONOOLEATE
♦ PEG SORBITAN OLEATE
♦ PEG-20 SORBITAN OLEATE
♦ POLYOXYETHYLENE (20) SORBITAN MONOOLEATE
♦ POLYOXYETHYLENE SORBITAN MONOOLEATE
♦ SORBITAN, MONO-9-OCTADECENOATE, POLY(OXY-1,2-ETHANEDIYL) DERIVS. (Z)-
♦ SORBITAN, MONOOLEATE, POLYOXYETHYLENE DERIVS.
Regulations in 21 CFR*: 172.515
172.623
172.840
173.340
175.105
175.300
178.3400
178.3750
73.1
73.1001

*Definitions

  • CAS Reg. No. (or other ID): Chemical Abstract Service (CAS) Registry Number© for the substance or a numerical code (other ID) assigned by CFSAN to those substances that do not have a CAS Registry Number (977nnn-nn-n or 809777nnn-nn-n series).
  • Substance: A name of the additive or impurity as recognized by CFSAN.
  • Calculation/Update Date: The date on which the CEDI was calculated or re-evaluated.
  • CDC: Cumulative Dietary Concentration (CDC, parts-per-billion, ppb)
  • CEDI: Cumulative Estimated Daily Intake (micrograms/kilogram body weight/person/day, µg/kg bw/d)
  • 21 CFR: The Code of Federal Regulations, Title 21 is the preferred reference to determine the regulatory status of Indirect Food Additives. Substances whose names appear in 21 CFR, parts 175-178 are authorized for specified intended users and conditions of use as stated in the regulation. Note that substances may appear in more than one regulation, or several times in the same regulation. Note that if a substance is mentioned in 21 CFR parts 175-178 and thus, is listed above, any other citations for the same substance in other sections of 21 CFR dealing with food additives (parts 1-199 inclusive) may also be cited.
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