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U.S. Department of Health and Human Services

Substances Added to Food (formerly EAFUS)

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The Substances Added to Food inventory replaces what was previously known as Everything Added to Foods in the United States (EAFUS).

The Substances Added to Food inventory includes the following types of ingredients regulated by the U.S. Food and Drug Administration (FDA):

  • Food additives and color additives that are listed in FDA regulations (21 CFR Parts 172, 173 and Parts 73, 74, 82 respectively), and flavoring substances evaluated by FEMA* and JECFA*.
    • Note that for a substance to be used as a color additive in the US, it must be authorized by a regulation in 21 CFR Part 73, 74, or 82.
  • Generally Recognized as Safe (“GRAS”) substances that are listed in FDA regulations (21 CFR Parts 182 and 184).
  • Substances approved for specific uses in foods prior to September 6, 1958, known as prior-sanctioned substances (21 CFR Part 181).
  • Substances formerly used:
    • Prohibited substances that are listed in FDA regulations (21 CFR Part 189) as prohibited from use in food (labeled as "PROHIBITED" or "PROHIBITED WITH EXCEPTIONS").
    • Delisted color additives in FDA regulations (21 CFR 81.10 and/or 81.30) (labeled as "DELISTED").
    • Some substances "no longer FEMA GRAS"

It is important to note that the inventory is only a partial list of food ingredients. Inclusion in this inventory of information from non-FDA entities does not indicate an FDA approval or evaluation of this use.

Users also have the option to search multiple food ingredient and packaging inventories at one time. This includes the following substances not listed in the Substances Added to Food inventory:

For more information, please refer to Food Ingredient and Packaging Inventories.


Search and display hints

  • Select the Substance name below to view the additional details about the substance.
  • To sort by a specific field, click on the column header for that field.
  • To browse the records, use the Show All, First/Previous/Next/Last, and Jump To options at the bottom of the data table.
  • To search for a specific term (or phrase or partial word), enter that term in the Search box and select Show Items to display only those records that contain the selected term.
  • The search results may include terms not shown on the results pages, but included in the full record descriptions. For example, a search for “gum Arabic” will find the substance “Acacia”.
  • The search results will return hits of records containing words that include the search term. For example, a search for the color red will return results that include terms such as reducing, ingredient, and denatured.
Download Substances Added to Food <em>(formerly EAFUS)</em> data in Microsoft Excel web format Download data from this searchable database in Excel format. If you need help accessing information in different file formats, see Instructions for Downloading Viewers and Players.
Search within these results
Records Found: 3971 Show All Page 14 of 80
CAS Reg. No.*
(or other ID)
Substance*
(sorted A-Z)
Used for*
(Technical Effect)
21 CFR*
977091-23-8 CINNAMON BARK OLEORESIN, CEYLON, CHINESE, OR SAIGON (CINNAMOMUM SPP.) FLAVORING AGENT OR ADJUVANT 182.20
8015-96-1 CINNAMON LEAF, OIL (CINNAMOMUM SPP.) FLAVORING AGENT OR ADJUVANT 182.20
977184-45-4 CINNAMON LEAF OIL, RECTIFIED 182.20
103-54-8 CINNAMYL ACETATE FLAVORING AGENT OR ADJUVANT 172.515
104-54-1 CINNAMYL ALCOHOL FLAVORING AGENT OR ADJUVANT 172.515
87-29-6 CINNAMYL ANTHRANILATE--PROHIBITED FLAVORING AGENT OR ADJUVANT 189.113
5320-75-2 CINNAMYL BENZOATE FLAVORING AGENT OR ADJUVANT 172.515
103-61-7 CINNAMYL BUTYRATE FLAVORING AGENT OR ADJUVANT 172.515
122-69-0 CINNAMYL CINNAMATE FLAVORING AGENT OR ADJUVANT 172.515
104-65-4 CINNAMYL FORMATE FLAVORING AGENT OR ADJUVANT 172.515
103-59-3 CINNAMYL ISOBUTYRATE FLAVORING AGENT OR ADJUVANT 172.515
140-27-2 CINNAMYL ISOVALERATE FLAVORING AGENT OR ADJUVANT 172.515
7492-65-1 CINNAMYL PHENYLACETATE FLAVORING AGENT OR ADJUVANT 172.515
103-56-0 CINNAMYL PROPIONATE FLAVORING AGENT OR ADJUVANT 172.515
6290-17-1 CIS- AND TRANS-ETHYL 2,4-DIMETHYL-1,3-DIOXOLANE-2-ACETATE FLAVORING AGENT OR ADJUVANT
83418-54-6 CIS- AND TRANS-5-ETHYL-4-METHYL-2-(2-BUTYL)-THIAZOLINE FLAVORING AGENT OR ADJUVANT
83418-53-5 CIS AND TRANS-5-ETHYL-4-METHYL-2-(2-METHYLPROPYL)-THIAZOLINE FLAVORING AGENT OR ADJUVANT
18433-93-7 CIS- AND TRANS-2-ISOBUTYL-4-METHYL-1,3-DIOXOLANE FLAVORING AGENT OR ADJUVANT
67879-60-1 CIS- AND TRANS-2-ISOPROPYL-4-METHYL-1,3-DIOXOLANE FLAVORING AGENT OR ADJUVANT
29725-66-4 CIS- AND TRANS-L-MERCAPTO-P-MENTHAN-3-ONE FLAVORING AGENT OR ADJUVANT
904929-41-5 (+/-)-CIS- AND TRANS-2-METHYL-2-(4-METHYL-3-PENTENYL)CYCLOPROPANECARBALDEHYDE FLAVORING AGENT OR ADJUVANT
59323-81-8 (+/-)CIS- AND TRANS-2-PENTYL-4-PROPYL-1,3-OXATHIANE FLAVORING AGENT OR ADJUVANT
57074-37-0 CIS-4-DECENOL FLAVORING AGENT OR ADJUVANT
6728-31-0 CIS-4-HEPTENAL FLAVORING AGENT OR ADJUVANT 172.515
1775-43-5 CIS-3-HEXENOIC ACID FLAVORING AGENT OR ADJUVANT
928-96-1 CIS-3-HEXEN-1-OL FLAVORING AGENT OR ADJUVANT 172.515
3681-71-8 CIS-3-HEXEN-1-YL ACETATE FLAVORING AGENT OR ADJUVANT
84434-20-8 CIS-3-HEXENYL ACETOACETATE FLAVORING AGENT OR ADJUVANT
16491-36-4 CIS-3-HEXENYL BUTYRATE FLAVORING AGENT OR ADJUVANT
61444-38-0 CIS-3-HEXENYL CIS-3-HEXENOATE FLAVORING AGENT OR ADJUVANT
33467-73-1 CIS-3-HEXENYL FORMATE FLAVORING AGENT OR ADJUVANT
31501-11-8 CIS-3-HEXENYL HEXANOATE FLAVORING AGENT OR ADJUVANT
55253-28-6 CIS-5-ISOPROPENYL-CIS-2-METHYLCYCLOPENTAN-1-CARBOXALDEHYDE FLAVORING AGENT OR ADJUVANT
10340-23-5 CIS-3-NONEN-1-OL FLAVORING AGENT OR ADJUVANT
693-80-1 CIS-9-OCTADECENYL ACETATE FLAVORING AGENT OR ADJUVANT
41653-97-8 CIS-5-OCTENOIC ACID FLAVORING AGENT OR ADJUVANT
5392-40-5 CITRAL FLAVORING AGENT OR ADJUVANT 182.60
7492-66-2 CITRAL DIETHYL ACETAL FLAVORING AGENT OR ADJUVANT 172.515
7549-37-3 CITRAL DIMETHYL ACETAL FLAVORING AGENT OR ADJUVANT 172.515
5694-82-6 CITRAL GLYCERYL ACETAL FLAVORING AGENT OR ADJUVANT
10444-50-5 CITRAL PROPYLENE GLYCOL ACETAL FLAVORING AGENT OR ADJUVANT 172.515
77-92-9 CITRIC ACID ANTIMICROBIAL AGENT,
ANTIOXIDANT,
ENZYME,
FLAVOR ENHANCER,
FLAVORING AGENT OR ADJUVANT,
LEAVENING AGENT,
PH CONTROL AGENT,
SEQUESTRANT,
SOLVENT OR VEHICLE,
SURFACE-ACTIVE AGENT
73.85
172.755
172.861
173.160
173.165
173.280
178.1010
184.1033
97593-31-2 CITRIC AND FATTY ACID ESTERS OF GLYCEROL FLAVORING AGENT OR ADJUVANT
106-23-0 CITRONELLAL FLAVORING AGENT OR ADJUVANT 172.515
8000-29-1 CITRONELLA, OIL (CYMBOPOGON NARDUS RENDLE) FLAVORING AGENT OR ADJUVANT 182.20
106-22-9 DL-CITRONELLOL FLAVORING AGENT OR ADJUVANT 172.515
7492-67-3 CITRONELLOXYACETALDEHYDE FLAVORING AGENT OR ADJUVANT 172.515
150-84-5 CITRONELLYL ACETATE FLAVORING AGENT OR ADJUVANT 172.515
68555-57-7 CITRONELLYL ANTHRANILATE FLAVORING AGENT OR ADJUVANT
141-16-2 CITRONELLYL BUTYRATE FLAVORING AGENT OR ADJUVANT 172.515

Show All 

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*Definitions

  • CAS Reg. No. (or other ID): Chemical Abstract Service (CAS) Registry Number® for the substance or a numerical code assigned by HFP to those substances that do not have a CAS Registry Number (977nnn-nn-n series).
  • Substance: The name of the ingredient as recognized by HFP.
  • Used for (Technical Effect): The physical or technical effect(s) the substance has in or on food; see 21 CFR 170.3(o) for definitions.
  • 21 CFR: Title 21 of the Code of Federal Regulations.
  • FEMA No.: The trade association, Flavor and Extract Manufacturers Association (FEMA), has established expert panels to evaluate and make independent determinations on the GRAS status of flavoring substances. The FEMA number is provided here as a reference to FEMA’s GRAS assessments.
  • JECFA: The Joint Expert Committee on Food Additives (JECFA) is an international expert scientific committee that is administered jointly by the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO). See JECFA Specifications for Flavourings <>

Color Additives

  • For a substance to be used as a color additive in the US, it must be authorized by a regulation in 21 CFR Part 73, 74, or 82.
CAS Reg. No.*
(or other ID)
Substance*
(sorted A-Z)
Used for*
(Technical Effect)
21 CFR*
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